Published Papers - MOTOYAMA Mitsugi

高齢高血圧症患者における低強度有酸素性トレーニングの降圧効果について(共著)

体力科学   30 ( 6 ) 818 - 823   1998

Exercise therapy in elderly hypertensive patient

Mitsugi Motoyama, Hiroaki Tanaka, Munehiro Shindo, Kikuo Arakawa

Japanese Journal of Physical Fitness and Sports Medicine ( Japanese Society of Physical Fitness and Sports Medicine )  47 ( 5 ) 473 - 488   1998

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大学生の身体組成と生活習慣

KATOU Hiroshi

和歌山大学教育学部教育実践研究指導センター紀要 ( Wakayama University )  第7巻   89～96頁 - 96   1997.08

肥満学生における６ｶ月間の運動習慣の違いが身体組成に及ぼす影響について

本山 貢, 加藤 弘, 矢野 勝, 松岡 勇二

和歌山大学教育学部教育実践研究指導センター紀要   第7巻   97～104頁 - 104   1997.08

DOI

高齢者の身体活動量の違いが最大酸素摂取量および血圧に及ぼす影響について

本山貢

和歌山大学教育学部紀要（自然科学）   第47集   57～66頁 - 66   1997.02

中高年者にみられる運動実践効果 －運動実践の呼吸循環機能と血圧、血中脂質に及ぼす効果－

Japanese Journal of Sports Science   第14巻1号   55～60頁   1995.02

THE EFFECTS OF LONG-TERM LOW-INTENSITY AEROBIC TRAINING AND DETRAINING ON SERUM-LIPID AND LIPOPROTEIN CONCENTRATIONS IN ELDERLY MEN AND WOMEN

M MOTOYAMA, Y SUNAMI, F KINOSHITA, T IRIE, J SASAKI, K ARAKAWA, A KIYONAGA, H TANAKA, M SHINDO

EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY AND OCCUPATIONAL PHYSIOLOGY ( SPRINGER VERLAG )  70 ( 2 ) 126 - 131   1995.02

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The effects of long-term low intensity aerobic training and detraining on serum lipid and lipoprotein concentrations were examined in 30 elderly men and women. These subjects were randomly divided into two groups. The training group [n = 15; 7 men and 8 women; mean age 75.5 (SD 5.6) years] agreed to take part in physical training using a treadmill with an exercise intensity at the blood lactate concentration threshold for 30 min 3-6 times a week for 9 months. The other group [n = 15; 7 men and 8 women; mean age 73.7 (SD 4.4) years] did not perform any particular physical training and was followed as the control. Following this training period the high density lipoprotein-cholesterol (HDL-C) had increased significantly (P<0.01) while the total cholesterol (TC):HDL-C ratio had decreased significantly (P<0.01) in the training group after 9 months but had not changed in the control group, The TC, triglyceride (TG) and low density lipoprotein-cholesterol (LDL-C) had not changed significantly in either group. No significant difference was seen between the groups throughout the period for TC, LDL-C or TG. There was, however, a significant correlation between the initial TC:HDL-C ratio and the change in the TC:HDL-C ratio following 3 months of training (P < 0.05). After 1 month of detraining in 5 patients, the HDL-C had decreased significantly (P < 0.05) while the TC:HDL-C had increased significantly in the training group (P < 0.01). These results suggested that long-term low intensity aerobic training improved the profile of serum lipid and lipoprotein concentrations, while detraining returned the profile to that of the pretraining levels in elderly persons.

高齢男女を対象とした低強度の有酸素性トレーニングが血清脂質およびリポ蛋白質濃度に及ぼす影響(共著)

体力科学   70 ( 2 ) 126 - 131   1995

長期間に及ぶ軽強度の有酸素的トレーニングと運動中止が有病高齢者の血清脂質及び脂質蛋白質に及ぼす影響について

体力科学   第43巻5号   434～442頁   1994.10  [Refereed]

Lactate Thresholdを指標とした長期トレーニングとその中止が薬物療法下の高齢な高血圧症患者の血圧に及ぼす影響について

体力科学   第43巻4号   300～308頁   1994.08  [Refereed]

健康スポーツの社会学 －地域健康管理システムの確立をめざして－

進藤宗洋

Journal of Integrated Medicine   第4巻5号   402～404頁 - 404   1994.05  [Refereed]

The effects of long-term mild aerobic training at lactate threshold and its cessation on blood pressure in older hypertensive patients under medication

Mitsugi Motoyama, Yoshiyuki Sunami, Fujihisa Kinoshita, Akira Kiyonaga, Hiroaki Tanaka, Munehiro Shindo, Takashi Irie

Japanese Journal of Physical Fitness and Sports Medicine   43 ( 4 ) 300 - 308   1994  [Refereed]

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After a general clinical observation period of 3 months, men and women from 66–82 yr. of age with hypertension (n=10) were studied to assess the effects of long-term mild aerobic training and detraining on their blood pressure. Ten patients agreed to take part in aerobic training using a treadmill with the intensity at the lactate threshold (LT) for 30 minutes 3–6 times a week for mean 17.1±9.8 months while the time course of changes in the resting blood pressure was monitored. Following the training period the LT increased significantly by the end of the training period (P&lt
0.001). After 3 months of training both the systolic and diastolic blood pressure decreased significantly (P&lt
0.05, respectively) and both blood pressures stabilized at a significantly lower level throughout the remainder of the study. The mean blood pressure decreased significantly for 9 months (P&lt
0.05). Finally, the systolic, mean and diastolic blood pressure were found to have decreased significantly, by 9, 5, 11 mmHg, respectively by the end of the training period. (SBP and MBP: P&lt
0.05, DBP: P&lt
0.01, respectively). One month after the training ended the systolic, mean and diastolic blood pressure all increased significantly (SBP and MBP: P&lt
0.001, DBP: P&lt
0.01, respectively) and approached the initial pre-training levels. In conclusion, the antihypertensive effect of mild aerobic training at the LT was confirmed for older patients taking antihypertensive medications. However, the cessation of such training resulted in a quick return to pre-training levels. © 1994, The Japanese Society of Physical Fitness and Sports Medicine. All rights reserved.

DOI

The effects of long-term low intensity aerobic training and the cessation of training on the serum lipid and lipoprotein concentrations in older patients

Mitsugi Motoyama, Yoshiyuki Sunami, Hujihisa Kinoshita, Akira Kiyonaga, Hiroaki Tanaka, Munehiro Shindo, Takashi Irie, Jun Sasaki

Japanese Journal of Physical Fitness and Sports Medicine   43 ( 5 ) 434 - 442   1994  [Refereed]

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The effects of long-term low intensity aerobic training and detraining on serum lipid and lipoprotein concentrations were examined in 10 older patients suffering from hypertension and coronary heart disease. Training was carried out for 30 minutes 3–6 times a week for a mean of 17.1 months using a treadmill with the intensity level set at the blood lactate threshold (LT). Following this training both LT and the serum HDL-c increased significantly (P&lt
0.001, P&lt
0.01, respectively) after 6 months while the TC/HDL-c ratio decreased singificantly (P&lt
0.001) only after 1 month and stabilized at a steady favorable value throughout the remainder of the study. The serum TC, TG and LDL-c did not change significantly by the end of the training period. There was a significant negative correlation between the initial TC/HDL-c level and the change in the TC/HDL-c level at 1 month after training (r=−0.71, P&lt
0.02). Only 1 month after the detraining the HDL-c decreased significantly while the TC/HDL-c increased in comparison with the final training value (P&lt
0.001, P&lt
0.05, respectively) and then returned to the pre-training levels. In conclusion, these results suggest that long-term low intensity aerobic training could improve the profile of the serum lipid and lipoprotein concentrations in older patients. However, these results might depend on such factors as a low HDL-c level, a high TG level, the length of the exercise period, or the frequency per week and the age of the patient, while the cessation of such training quickly returned the profile to that of pre-training levels. © 1994, The Japanese Society of Physical Fitness and Sports Medicine. All rights reserved.

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Angiotensin II formation by an alternative pathway during exercise in humans

Shin-ichiro Miura, Munehito Ideishi, Takaaki Sakai, Mitsugu Motoyama, Akio Kinoshita, Manabu Sasaguri, Hiroaki Tanaka, Munehiro Shindo, Kikuo Arakawa

Journal of Hypertension   12 ( 10 ) 1177 - 1181   1994  [Refereed]

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Objective: We postulated a ‘kinin-tensin system’ in which angiotensin II (Ang II) is cleaved by one or more serine protease independent of renin or angiotensin converting enzyme (ACE). The aim was to determine whether this alternative Ang ll-forming pathway by serine proteases participates in the rise in plasma levels of Ang II during exercise in humans. Design and methods: The study consisted of two double-blind crossover experiments. In experiment 1 six healthy volunteers who had been taking either placebo (group P) or the ACE inhibitor captopril (150mg/day for 3 days
group C) performed a cycle ergometer graded exercise test at four different exercise intensities: stage 1, half of the intensity at the blood lactate threshold (W&lt
inf&gt
LT&lt
/inf&gt
)
stage 2, the intensity at W&lt
inf&gt
LT&lt
/inf&gt

stage 3, the intensity at 4mmol/l blood lactate
and stage 4, an intensity between stage 3 and maximum intensity. In experiment 2 the same volunteers took captopril (150mg/day for 3 days) and performed exercise at an intensity corresponding to 90% of the 4 mmol/l blood lactate intensity for 30 min during intravenous drip injection of a serine protease inhibitor, nafamostat [NAF
0.2 mg/kg per h
NAF(+) group] or saline [NAF(-) group]. Results: In experiment 1 plasma Ang II levels increased from at rest to after exercise in both groups P and C. Although there was a significant treatment effect, captopril did not significantly alter the exercise-induced changes in Ang II level. In experiment 2 the increase in Ang II level after 30 min exercise in the NAF(+) group was significantly lower than in the NAF(-) group. Conclusions: These results suggest the presence of an alternative Ang ll-forming pathway independent of ACE, and that one or more NAF-sensitive serine protease is responsible, at least partly, for generating Ang II during exercise. © Current Science Ltd.

日常的に運動を継続させるための社会的因子の研究～エアロビックダンス・インストラクターを長期間継続している中年女性を通しての考察～

ふくおか医療社会事業のあゆみ   第20号   69～79頁   1993.03

高血圧の運動療法

臨床スポーツ医学   10   438 - 443   1993

9ヶ月間に及ぶ軽強度の有酸素的運動が65才以上の高血圧症を有する高齢男女の血中脂質及びリポ蛋白に及ぼす影響について

体力科学   第41巻5号   559～566頁   1992.10  [Refereed]

Aerobic Dance Instructorの血清脂質およびアポリポ蛋白濃度と有酸素的作業能との関連性と経時的変化

本山貢

臨床スポーツ医学   第9巻4号   442～447頁 - 447   1992.04  [Refereed]

運動負荷心電図の非特異的なST-T変化と推定最大酸素摂取量との関連について －健常女性についての検討－

動脈硬化   第20巻1号   31～35頁   1992.01  [Refereed]

Relationship between nonspecific ST-T changes in exercise ECG and predicted maximal oxygen intake in Japanese females

M. Motoyama, T. Irie, J. Wada, Y. Aritomi, A. Setoyama, H. Saku, Y. Sunami, H. Tanaka, M. Shindo

Journal of Japan Atherosclerosis Society   20 ( 1 ) 31 - 35   1992  [Refereed]

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